Genome-wide inference of natural selection on human transcription factor binding sites

Keinan lab postdoc Leonardo Arbiza led a study recently published in Nature Genetics that demonstrates that evolutionary changes in transcription factor binding sites significantly contribute to changes in gene expression associated with adaptations in humans.

Nature Genetics: http://www.nature.com/ng/journal/v45/n7/full/ng.2658.html  PDF here

Cornell Chronicle: http://news.cornell.edu/stories/2013/06/genetic-switches-play-big-role-h...

3CPG: http://3cpg.cornell.edu/index.cfm/news.details?newsID=872

Faculty of 1000: http://f1000.com/prime/718018456