Recent & Selected Publications

  1. K. Ye, F. Gao, D. Wang, O. Bar-Yosef, A. KeinanDietary adaptation of FADS genes in Europe varied across time and geography. Nature Ecology and Evolution. (2017)
  2. Y. Pinto, O. Gabay, L. Arbiza, A.J. Sams, A. Keinan^, E.Y. Levanon^. Clustered mutations in hominid genome evolution are consistent with APOBEC3G enzymatic activity. Genome Research, 26(5): 579-87 (2016)
  3. K.S.D. Kothapalli*, K. Ye*, M.S. Gadgil, S.E. Carlson , K.O. O'Brien, J.Y.Zhang, H.G. Park, K. Ojukwu, J. Zou, S.S. Hyon, K.S. Joshi, Z. Gu, A. Keinan^, J.T. Brenna^. Positive selection on a regulatory insertion-deletion polymorphism in FADS2 influences apparent endogenous synthesis of arachidonic acid. Molecular Biology and Evolution, 33(7):1726-39 (2016)  
  4. Y. WaldmanA. Biddanda, M. Dubrovsky, C. Campbell, C. Oddoux, E. Friedman, G. Atzmon, E. Halperin, E. Halperin, H. Ostrer, A. KeinanThe genetic history of Cochin Jews from India. Human Genetics, 135(10):1127-43 (2016)
  5. F. Gao, A. Keinan. Inference of Super-exponential Human Population Growth via Efficient Computation of the Site Frequency Spectrum for Generalized ModelsGenetics, 202: 235-245 (2016) 
  6. A. Slavney, L. Arbiza, A.G. Clark^, A. Keinan^. Strong Constraint on Human Genes Escaping X-Inactivation Is Modulated by their Expression Level and Breadth in Both Sexes. Molecular Biology and Evolution, 33(2): 384-393 (2015)
  7. F. Gao*, D. Chang*, A. Biddanda*, L. Ma, Y. Guo, Z. Zhou, A. KeinanXWAS: a toolset for genetic data analysis and association studies of the X chromosomeJournal of Heredity, 106(5): 6 (2015)
  8. L. Arbiza*, S. Gottipati*, A. Siepel, A. Keinan.  Contrasting X-linked and autosomal diversity across 14 human populationsAmerican Journal of Human Genetics, 94(6):827-44 (2014).
  9. E. Gazave*, L. Ma*, D. Chang*, A. Coventry, F. Gao, D. Muzny, E. Boerwinkle, R. Gibbs, C. F. Sing, A. G. Clark, A. Keinan.  Neutral genomic regions refine models of recent rapid human population growth. Proceedings of the National Academy of Sciences, 11, 757-762 (2014).
  10. K. Ye, J. Lu, F. Ma, A. Keinan, Z. Gu. Extensive pathogenicity of mitochondrial heteroplasmy in healthy human individuals. Proceedings of the National Academy of Sciences, 111(29):10654-10659 (2014)  
  11. L. Ma, A. G. Clark, A. Keinan. Gene-Based Testing of Interactions in Association Studies of Quantitative Traits. PLoS Genetics, 9, e1003321 (2013).
  12. L. Arbiza, I. Gronau,  B.A. Aksoy, M.J. Hubisz, B. Gulko, A. Keinan, A. Siepel. Genome-wide inference of natural selection on human transcription factor binding sites. Nature Genetics, 45:723–729 (2013) (Supplementary Information)
  13. A. Keinan, A. G. Clark. Recent explosive human population growth has resulted in an excess of rare genetic variants. Science, 336, 740-743 (2012). (Supplementary information)